Srijit Seal
Principal Scientist, Human Chemical Company
Visiting Researcher, Uppsala University
Selected posts
| Title | |||
|---|---|---|---|
|
Scaling AI for drug discovery
Questions about the quality of future discoveries, as well as their number. Srijit Seal, AI |
36 | 22558 | |
|
Defining AI, LLM, and QSAR for scientific audiences
Late-night slide preparation and familiar requests from reviewers. Srijit Seal, Scientific practice |
79 | 52685 | |
|
Scientist salaries and working hours in biotech
Questions about pay and working-hour expectations in startup job postings. Srijit Seal, Careers |
89 | 47455 | |
|
Model validation for small-molecule drug discovery
The Polaris collaboration on testing whether models generalize to new chemistry. Srijit Seal, Research |
388 | 26571 | |
|
Artificial intelligence in drug discovery: where we stand
Our Perspective in Nature Reviews Drug Discovery on the current state of AI in the field. Srijit Seal, Research |
993 | 54181 | |
|
Evaluating LLM-generated benchmarks
Reflections on reviewing datasets and evaluations for NeurIPS. Srijit Seal, Scientific practice |
386 | 52997 | |
|
Fabricated references in scientific papers
Reference managers, DOI checks, and the responsibility to verify citations. Srijit Seal, Scientific practice |
187 | 84816 | |
|
Lessons from the OpenADMET PXR challenge
Using Codex while thinking through assay biology, validation, and activity cliffs. Srijit Seal, AI |
210 | 22069 | |
|
AI and computational chemistry job opportunities
An April 2026 collection of positions in pharma and biotech. Some roles may now be closed. Srijit Seal, Careers |
153 | 19770 | |
|
Cell Painting in primary human hepatocytes
Our Cell Systems paper on cytotoxicity and mode-of-action analysis. Srijit Seal, Research |
388 | 28093 | |
|
Roles in cheminformatics, ADMET, and computational chemistry
A March 2026 collection of positions in pharma and biotech. Some roles may now be closed. Srijit Seal, Careers |
252 | 25837 | |
|
AI agents in drug discovery, published in Drug Discovery Today
The published review of applications and case studies from academia and industry. Srijit Seal, Research |
242 | 20900 | |
|
Best Paper Award for toxicity prediction guidelines
Recognition from the SOT Regulatory and Safety Evaluation Specialty Section. Srijit Seal, Research |
332 | 17560 | |
|
Reflections on my time at Merck
What I learned from colleagues across discovery science and computational toxicology. Srijit Seal, Careers |
340 | 24885 | |
|
The quality of scientific peer review
A reflection on factual errors in reviews and the use of AI by reviewers. Srijit Seal, Scientific practice |
68 | 18009 | |
|
Cell count as a bioactivity benchmark
Our Nature Communications paper on cell count, cytotoxicity, and benchmark design. Srijit Seal, Research |
400 | 39026 | |
|
What very small p values tell us
Statistical precision, model assumptions, and real-world sources of error. Srijit Seal, Scientific practice |
37 | 28784 | |
|
AI agents in drug discovery: a review with industry case studies
A collaboration between researchers, startups, and venture partners. Srijit Seal, Research |
503 | 43243+ | |
|
arXiv policies for review articles
A discussion of preprint policies and concerns about LLM-generated submissions. Srijit Seal, Scientific practice |
109 | 30662+ | |
|
Unrealistic experience requirements in AI jobs
A job asking for more years of PyTorch experience than PyTorch has existed. Srijit Seal, Careers |
334 | 56919+ | |
|
An open reading link for our Cell Painting review
Sharing a free reading link and thanking the review's co-authors. Srijit Seal, Research |
179 | N/A | |
|
When plate layout predicts toxicity
Why imaging models need comparisons against technical controls. Srijit Seal, Scientific practice |
115 | N/A | |
|
Cell Painting: a decade of discovery and innovation
Our Nature Methods review of the assay, its applications, and the community using it. Srijit Seal, Research |
225 | N/A | |
|
Foundation models at the Cambridge Cheminformatics Meeting
An invitation to discuss foundation models for non-clinical safety. Srijit Seal, Events |
6 | N/A | |
|
AI models for drug discovery
Models for liver toxicity, cardiotoxicity, cell imaging, and pharmacokinetics. Srijit Seal, Research |
138 | N/A | |
|
BioMorph: interpreting Cell Painting features
Linking image-based profiling to biological measurements and sharing ML-ready datasets. Srijit Seal, Research |
104 | N/A | |
|
Understanding Biology in the Age of Artificial Intelligence
Announcing the June 2023 conference at the University of Cambridge. Srijit Seal, Events |
70 | N/A | |
|
An MPhil graduation at Clare Hall
Celebrating a postponed graduation ceremony and the support behind my research. Srijit Seal, Careers |
173 | N/A |
No posts match your search.
Post impressions cover the available export periods. A + marks a lower bound where an export lacks that post; N/A means no verified count.
Selected posts, not a complete archive. Titles and summaries are edited for this page. Each title links to the original.